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| 產(chǎn)地 | 進(jìn)口、國(guó)產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號(hào) | CS11454 |
| 應(yīng)用范圍 | ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
| CAS編號(hào) | |
| 抗體名 | Anti-Tex14/CT113 |
| 克隆性 | |
| 靶點(diǎn) | 詳見(jiàn)說(shuō)明書(shū) |
| 適應(yīng)物種 | 詳見(jiàn)說(shuō)明書(shū) |
| 形態(tài) | 詳見(jiàn)說(shuō)明書(shū) |
| 宿主 | 詳見(jiàn)說(shuō)明書(shū) |
| 亞型 | IgG |
| 標(biāo)識(shí)物 | 詳見(jiàn)說(shuō)明書(shū) |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from Human Tex14/CT113 (1-100aa) |
中文名稱(chēng) 癌/睪丸抗原113抗體規(guī)格
英文名稱(chēng) Anti-Tex14/CT113
別 名 Cancer/testis antigen 113; CT113; Inactive serine/threonine protein kinase TEX14; SGK307; Protein kinase like protein SgK307; Sugen kinase 307; Testis expressed Protein 14; Testis expressed sequence 14; Testis expressed sequence 14 protein; TEX14_HUMAN.
產(chǎn)品屬性：
癌/睪丸抗原113抗體規(guī)格 濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來(lái)源 Rabbit
克隆類(lèi)型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Horse, Sheep
產(chǎn)品類(lèi)型 一抗
研究領(lǐng)域 發(fā)育生物學(xué) 干細(xì)胞
蛋白分子量 predicted molecular weight: 168kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from Human Tex14/CT113 (1-100aa)
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
癌/睪丸抗原113抗體規(guī)格 產(chǎn)品應(yīng)用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 TEX14 is a 1,497 amino acid protein that belongs to the protein kinase superfamily and is expressed in testis. The gene encoding TEX14 is located on chromosome 17 and is required for spermatogenesis and normal structure of the intercellular bridge that connects spermatocytes and spermatogonia. TEX14 co-localizes with the centralspindlin complex, MKLP-1 (mitotic kinesin-like protein 1) and male germ cell Rac GTPase (Rac GTPase-activating protein) and converts these midbody matrix proteins into stable intercellular bridge components. TEX14 contains 3 ANK repeats and 1 protein kinase domain. Three isoforms exist due to alternative splicing events.
Function : Testis-expressed gene 14 (TEX14) is a novel protein that localizes to germ cell intercellular bridges. In the absence of TEX14, intercellular bridges are not observed. Spermatogenesis in Tex14–/– mice progresses through the transit amplification of diploid spermatogonia and the expression of early meiotic markers but halts before the completion of the first meiotic division.
Subunit : Interacts with KIF23 and RBM44. Interacts with CEP55; inhibiting interaction between CEP55 and PDCD6IP/ALIX and TSG101
Subcellular Location : Cytoplasm (By similarity). Midbody (By similarity). Chromosome, centromere, kinetochore (By similarity). Note=Detected in the intercellular bridges that connect male germ cell daughter cells after cell division (By similarity).
Tissue Specificity : Detected in testis.
Post-translational modifications : Phosphorylated on Thr residues by CDK1 during early phases of mitosis, promoting the interaction with PLK1 and recruitment to kinetochores. Phosphorylated on Ser-437 by PLK1 during late prometaphase promotes the rapid depletion from kinetochores and its subsequent degradation by the APC/C complex.
Similarity : Belongs to the protein kinase superfamily.
Contains 3 ANK repeats.
Contains 1 protein kinase domain.
Database links : UniProtKB/Swiss-Prot: Q8IWB6.2
實(shí)驗(yàn)流程：
全、新、優(yōu)、品、好四大特點(diǎn)：
癌/睪丸抗原113抗體規(guī)格 全：公司提供上萬(wàn)種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細(xì)胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì)，產(chǎn)品一旦售出，實(shí)驗(yàn)過(guò)程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時(shí)沒(méi)有任何的后顧之憂。
技術(shù)外包服務(wù):
★癌/睪丸抗原113抗體規(guī)格 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測(cè)序、載體構(gòu)建等
★蛋白工程：原核、哺乳動(dòng)物蛋白表達(dá)系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細(xì)胞工程：細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。
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