|
| 產(chǎn)地 | 進口、國產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號 | CS10969 |
| 應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 |
| CAS編號 | |
| 抗體名 | Anti-RNF41 |
| 克隆性 | |
| 靶點 | 詳見說明書 |
| 適應(yīng)物種 | 詳見說明書 |
| 形態(tài) | 詳見說明書 |
| 宿主 | 詳見說明書 |
| 亞型 | IgG |
| 標識物 | 詳見說明書 |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human RNF41 |
環(huán)指蛋白41抗體費用 英文名稱 Anti-RNF41
中文名稱 環(huán)指蛋白41抗體費用
別 名 E3 ubiquitin protein ligase NRDP1; Fetal Liver RING finger protein; FLRF; MGC45228; Neuregulin receptor degradation protein 1; NRDP1; Ring Finger Protein 41; SBBI03; RNF41_HUMAN.
產(chǎn)品屬性：
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Cow, Sheep
產(chǎn)品類型 一抗
研究領(lǐng)域 細胞生物 免疫學
蛋白分子量 predicted molecular weight: 36kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human RNF41
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
環(huán)指蛋白41抗體費用 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 RNF41 contains one RING-type zinc finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. It acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins, such as ERBB3. RNF41 has been detected in ovary, testis and prostate.
Function : Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88 and Negatively regulates MYD88-dependent production of proinflammatory cytokines but can promote TRIF-dependent production of type I interferon. Promotes also activation of TBK1 and IRF3. Involved in the ubiquitination of erythropoietin (EPO) and interleukin-3 (IL-3) receptors. Thus, through maintaining basal levels of cytokine receptors, RNF41 is involved in the control of hematopoietic progenitor cell differentiation into myeloerythroid lineages (By similarity). Contributes to the maintenance of steady-state ERBB3 levels by mediating its growth factor-independent degradation. Involved in the degradation of the inhibitor of apoptosis BIRC6 and thus is an important regulator of cell death by promoting apoptosis. Acts also as a PARK2 modifier that accelerates its degradation, resulting in a reduction of PARK2 activity, influencing the balance of intracellular redox state.
Subunit : Interacts with USP8, ERBB3, PARK2 and BIRC6. Interacts with CSF2RB, EPOR, IL3RA, MYD88 and TBK1 (By similarity).
Tissue Specificity : Detected in ovary, testis and prostate.
Post-translational modifications : Autoubiquitinated. Autoubiquitination leads to proteasomal degradation. Deubiquitinated by USP8 to get stabilized which induces apoptosis.
Similarity : Contains 1 RING-type zinc finger.
Contains 1 SIAH-type zinc finger.
Database links : UniProtKB/Swiss-Prot: Q9H4P4.2
實驗流程：
全、新、優(yōu)、品、好四大特點：
環(huán)指蛋白41抗體費用 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標準品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。
正在熱銷的相關(guān)產(chǎn)品：
Anti-phospho-SHC (Tyr349) /FITC 熒光素標記磷酸化SH2結(jié)構(gòu)域轉(zhuǎn)化蛋白1抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Apaf-1 (Apoptosis protease activating factor-1)(NT) 凋亡蛋白活性因子-1(抗原)Multi-class antibodies規(guī)格： 0.5mg
中分子量神經(jīng)絲蛋白抗體 Anti-NF-M 0.1ml
Stra8 英文名稱： 視黃酸激活基因8抗體 0.1ml
ELK1 英文名稱： 細胞轉(zhuǎn)錄因子ELK1抗體 0.1ml
Rhesus antibody Rh Phospho-p90RSK (Thr573) 磷酸化絲氨酸/蘇氨酸激酶p90RSK蛋白抗體 規(guī)格 0.1ml
Apaf-1 (Apoptosis protease activating factor-1)(NT) 凋亡蛋白活性因子-1(抗原)Multi-class antibodies規(guī)格： 0.5mg
Anti-Plexin A2/FITC 熒光素標記神經(jīng)叢蛋白A2抗體IgGMulti-class antibodies規(guī)格： 0.2ml
優(yōu)級胎血清Multi-class antibodies規(guī)格： 200ml
同源盒基因的一種 Anti-HOXc8 0.2ml
Donkey anti-Rabbit IgG whole serum 驢抗兔IgG抗血清 1ml
FOS B 英文名稱： FosB蛋白抗體 0.1ml
Rhesus antibody Rh phospho-REC8(Ser251) 磷酸化減數(shù)分裂重組蛋白家族REC8抗體 規(guī)格 0.1ml
優(yōu)級胎血清Multi-class antibodies規(guī)格： 200ml
leptin 小鼠瘦素Multi-class antibodies規(guī)格： 48T
Anti-human Fibrinogen 人纖維蛋白原抗體Multi-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh Mouse Anti-Rabbit IgM/Alexa Fluor 350 Alexa Fluor 350標記的小鼠抗兔IgM 規(guī)格 0.1ml
人高香草酸(HVA) ELISA Kit 人高香草酸 96T
Sumo 2 英文名稱： 泛素樣蛋白Sumo2抗體 0.2ml
CDK2AP2 英文名稱： 細胞周期素依賴激酶2相關(guān)蛋白2抗體 0.2ml
Anti-human Fibrinogen 人纖維蛋白原抗體Multi-class antibodies規(guī)格： 0.2ml
HE瓊脂(HE)250g用于沙門氏菌的選擇性分離培養(yǎng)(GB標準)
JMMediumBase
噻孢霉素 A 1.25μg/支*5 添加于100ml HB0121中
RNS培養(yǎng)基250g/瓶用于植物組織培養(yǎng)incubationmediaRNS培養(yǎng)基250g/瓶用于植物組織培養(yǎng)
黃素 3.0mg/支*5 每支添加于225ml HBJ005中制成LB1肉湯
SoybeanCaseinDigestMedium
金黃色葡萄球菌顯色培養(yǎng)基 1000mL/瓶 incubation media 金黃色葡萄球菌顯色培養(yǎng)基 1000mL/瓶
肉浸液肉湯 250g 用于金黃色葡萄球菌、溶血性鏈球菌和蠟樣芽孢桿菌的培養(yǎng)(GB標準)
瓊脂培養(yǎng)基HAgarmediumH(MacConkeyagar)用于腸道致病菌的選擇性分離培養(yǎng)。
LBSagar
環(huán)指蛋白41抗體費用 伊紅美藍瓊脂(EMB) 1000(g) incubation media 伊紅美藍瓊脂(EMB) 1000(g)
營養(yǎng)肉湯(NB) 250(g) incubation media 營養(yǎng)肉湯(NB) 250(g)
營養(yǎng)肉湯(NB) 1000(g) incubation media 營養(yǎng)肉湯(NB) 1000(g)
營養(yǎng)瓊脂(NA) 250(g) incubation media 營養(yǎng)瓊脂(NA) 250(g)
技術(shù)外包服務(wù):
★環(huán)指蛋白41抗體費用 分子生物學：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學：基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細胞工程：細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。
|
|
|
|
