|
| 產(chǎn)地 | 進口、國產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號 | CS10239 |
| 應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 |
| CAS編號 | |
| 抗體名 | Anti-p55/DCAF1 |
| 克隆性 | |
| 靶點 | 詳見說明書 |
| 適應(yīng)物種 | 詳見說明書 |
| 形態(tài) | 詳見說明書 |
| 宿主 | 詳見說明書 |
| 亞型 | IgG |
| 標識物 | 詳見說明書 |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human p55/DCAF1 |
全、新、優(yōu)、品、好四大特點：
染色質(zhì)組裝因子1P55抗體品牌 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標準品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。
染色質(zhì)組裝因子1P55抗體品牌 英文名稱 Anti-p55/DCAF1
中文名稱 染色質(zhì)組裝因子1P55抗體品牌
別 名 Caf 1; CAF-1; CAF-1 P55 subunit; CAF1 p55 subunit; CAF1A; CAF1P55; chaf1b; Chromatin assembly factor 1 p55 subunit; Chromatin assembly factor 1 p60 subunit; chromatin assembly factor 1 subunit; Chromatin assembly factor I; dCAF-1; dCAF1; Human chromatin assembly factor-I p55 subunit; Nucleosome remodeling factor 55 kDa subunit; NURF 55; NURF-55; p55; Probable histone binding protein Caf1; VPRBP_HUMAN.
產(chǎn)品屬性：
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Rabbit
產(chǎn)品類型 一抗
研究領(lǐng)域 細胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
蛋白分子量 predicted molecular weight: 169kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human p55/DCAF1
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
染色質(zhì)組裝因子1P55抗體品牌 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 P55 is an extensively palmitoylated erythrocyte membrane protein, and a member of the MAGUK family. P55 also resists salt extraction, resulting in a high affinity for the plasma membrane. P55 contains a PDZ/DHR domain, a conserved SH-3 domain that appears to suppress tyrosine kinase activity of various oncoproteins, a 39-amino acid motif that binds to cytoskeletal protein 4.1R, and a guanylate kinase-like domain. Interaction with glycophorin C (GPC) and 4.1R suggests that p55 may play a role in the dynamic regulation in the erythrocyte membrane. In addition, p55 gene expression in vivo may be associated with a CpG island. P55 is constitutively expressed in K562 erythroleukemia cells during erythropoiesis and undergoes a 2-fold amplification after induction.
Function : Component of the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex, VprBP/DCAF1 may function as the substrate recognition module within this complex. For example, VprBP/DCAF1 targets NF2 to the E3 ubiquitin-ligase complex for ubiquitination and subsequent proteasome-dependent degradation. In case of infection by HIV-1 virus, it is recruited by HIV-1 Vpr in order to hijack the CUL4A-RBX1-DDB1 function leading to arrest the cell cycle in G2 phase, and also to protect the viral protein from proteasomal degradation by another E3 ubiquitin ligase. In case of infection by HIV-2 virus, it is recruited by HIV-2 Vpx in order to hijack the CUL4A-RBX1-DDB1 function leading to enhanced efficiency of macrophage infection and promotion of the replication of cognate primate lentiviruses in cells of monocyte/macrophage lineage. Associated with chromatin in a DDB1-independent and cell cycle-dependent manner, VprBP/DCAF1 is recruited to chromatin as DNA is being replicated and is released from chromatin before mitosis.
Subunit : Component of the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex that could interact with HIV-1 virus Vpr protein and HIV-2 virus Vpx protein. Interacts directly with DDB1. Also forms a ternary complex with DDA1 and DDB1. Interacts with NF2 (via FERM domain). Component of EDD/UBR5-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and VPRBP proteins (EDVP complex). Interacts directly with DYRK2.
Subcellular Location : Cytoplasm. Nucleus.
Similarity : Belongs to the VPRBP/DCAF1 family.
Contains 1 LisH domain.
Contains 5 WD repeats.
Database links : UniProtKB/Swiss-Prot: Q9Y4B6.3
實驗流程：
正在熱銷的相關(guān)產(chǎn)品：
HSCCAg-2(uman Squamous Cell Carcinoma Antigen 2) ELISA Kit 人細胞癌抗原2Multi-class antibodies規(guī)格： 48T
Anti-HO-2 血紅素氧合酶2抗體Multi-class antibodies規(guī)格： 0.1ml
Rhesus antibody Rh MCP-2/CCL8 單核細胞趨化蛋白2抗體 規(guī)格 0.2ml
PDI(Human Protein disulfide-isomerase precursor) ELISA Kit 人蛋白二硫化物異構(gòu)酶前體 96T
RBMX2 英文名稱： RNA結(jié)合蛋白X-連鎖蛋白2抗體 0.1ml
C1orf124 英文名稱： 1號染色體開放閱讀框124抗體 0.2ml
Anti-HO-2 血紅素氧合酶2抗體Multi-class antibodies規(guī)格： 0.1ml
FGF-6 human 人成纖維生長因子-6Multi-class antibodies規(guī)格： 48T
Anti-CNGA2 環(huán)核苷酸陽離子通道蛋白α2抗體Multi-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh NOX4/NADPH oxidase 4 NADPH氧化酶4抗體 規(guī)格 0.1ml
human HMGB-1 ELISA Kit 人高遷移率族蛋白B1 ELISA Kit 96T
TMEM16A 英文名稱： 跨膜蛋白16A/鈣激活氯離子通道抗體 0.1ml
C7orf34 英文名稱： 7號染色體開放閱讀框34抗體 0.2ml
Anti-CNGA2 環(huán)核苷酸陽離子通道蛋白α2抗體Multi-class antibodies規(guī)格： 0.2ml
Anti-KLK10/FITC 熒光素標記激肽釋放酶10抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Anti-Smac/DIABLO/FITC 熒光素標記線粒體促凋亡蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh ALK/CD246 間變型激酶抗體 規(guī)格 0.2ml
Rabbit Anti-human IgG/Cy5.5 Cy5.5標記的兔抗人IgG 0.1ml
GLYCTK 英文名稱： HBeAg結(jié)合蛋白4/甘油激酶抗體 0.2ml
Rhesus antibody Rh Rabbit Anti-Guinea pig IgG/RBITC 羅丹明標記的兔抗豚鼠IgG 規(guī)格 0.3ml
Anti-Smac/DIABLO/FITC 熒光素標記線粒體促凋亡蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml
大鼠磷酸化腺苷酸活化蛋白激酶(AMPK)ELISA試劑盒 ，英文名： AMPK ELISA Kit
人血小板因子4(PF-4/CXCL4)ELISA檢測試劑盒HumanPlateletFactor4,PF-4ELISAKit 96T/48T
蜥蜴17羥孕酮(17-OHP)免疫試劑盒 Lizard 17-Hydroxyprogesterone,17-OHP ELISA kit
CLIAKitforOxLDL(Humanoxidizedlowdensitylipoprotein)ELISAKit人氧化規(guī)格：48T/96T
隨機引物DNA探針同位素([α32P]dCTP)聚合酶標記試劑盒20次
ELISAKitIL-1sRⅡ人白介素1可溶性受體Ⅱ規(guī)格：48T/96T
大鼠表皮調(diào)節(jié)素(EREG)ELISA試劑盒 ，英文名： EREG ELISA Kit
Rat female three alcohol (E3) ELISA Kit 大鼠雌三醇(E3)ELISA試劑盒
RatIerleukin-2receptor,IL-2RELISAkit 大鼠白介素2受體(IL-2R)ELISA試劑盒 96T/48T 進口分裝
COXIgG柯薩奇病毒IgG混合型(間接法二步法)
細胞乙脫氫酶1活性比色法定量檢測試劑盒20次
RatCollageypeⅡ,ColⅡELISAKit大鼠Ⅱ型膠原(ColⅡ)ELISA試劑盒規(guī)格：96T/48T
染色質(zhì)組裝因子1P55抗體品牌 大鼠蛋白激酶Bβ(PKBβ)ELISA試劑盒 ，英文名： PKBβ ELISA Kit
Rat ierleukin 27 (IL-27) ELISA Kit 大鼠白介素27(IL-27)ELISA試劑盒
RatC-ReactiveProtein,CRPELISAKit 大鼠C反應(yīng)蛋白(CRP)ELISA試劑盒 96T/48T 進口分裝
CLIAKitforCVNPF(HumanCobravenomneuronalprotectivefactor)ELISAKit人神經(jīng)保護因子規(guī)格：48T/96T
細胞衰老特異性晚期脂褐素堿性品紅(ZIEHL-NEELSEN)原位染色試劑盒50次
RatEsiol,E3ELISAKit大鼠雌三醇(E3)ELISA試劑盒規(guī)格：96T/48T
技術(shù)外包服務(wù):
★染色質(zhì)組裝因子1P55抗體品牌 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細胞工程：細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。
|
|
|
|
