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2'-5'-寡腺苷酸合成酶2抗體規(guī)格
  • 品牌:上海莼試
  • 產(chǎn)地:進(jìn)口、國(guó)產(chǎn)
  • 貨號(hào):CS10110
  • 發(fā)布日期: 2018-12-28
  • 更新日期: 2025-05-14
產(chǎn)品詳請(qǐng)
產(chǎn)地 進(jìn)口、國(guó)產(chǎn)
品牌 上海莼試
保存條件 Store at -20 °C
貨號(hào) CS10110
應(yīng)用范圍 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
CAS編號(hào)
抗體名 Anti-OAS2
克隆性
靶點(diǎn) 詳見(jiàn)說(shuō)明書
適應(yīng)物種 詳見(jiàn)說(shuō)明書
形態(tài) 詳見(jiàn)說(shuō)明書
宿主 詳見(jiàn)說(shuō)明書
亞型 IgG
標(biāo)識(shí)物 詳見(jiàn)說(shuō)明書
濃度 1mg/1ml%
免疫原 KLH conjugated synthetic peptide derived from human OAS2

中文名稱  2'-5'-寡腺苷酸合成酶2抗體規(guī)格 

英文名稱  Anti-OAS2

     (2-5'')oligo(A) synthase 2; (2-5')oligo(A) synthetase 2; 2''-5''-oligoadenylate synthase 2; 2'-5'-oligoadenylate synthetase 2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; 2-* synthase 2; 2-* synthetase 2; MGC78578; OAS2; OAS2_HUMAN; p69 OAS / p71 OAS; p69OAS / p71OAS.

產(chǎn)品屬性:

2'-5'-寡腺苷酸合成酶2抗體規(guī)格       1mg/1ml

規(guī)   0.2ml/200μg

抗體來(lái)源  Rabbit

克隆類型   polyclonal

交叉反應(yīng)   Human, Mouse, Dog, Pig

產(chǎn)品類型   一抗  

研究領(lǐng)域    細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號(hào) 線粒體

蛋白分子量  predicted molecular weight: 82kDa 

       Lyophilized or Liquid

  KLH conjugated synthetic peptide derived from human OAS2

      IgG

純化方法   affinity purified by Protein A

儲(chǔ)    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

2'-5'-寡腺苷酸合成酶2抗體規(guī)格 產(chǎn)品應(yīng)用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

(石蠟切片需做抗原修復(fù)) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產(chǎn)品介紹 This gene encodes a member of the 2-* synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-*s). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

Function : Interferon-induced, dsRNA-activated antiviral enzymewhich plays a critical role in cellular innate antiviral response.In addition, it may also play a role in other cellular processessuch as apoptosis, cell growth, differentiation and generegulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates(2-*) from ATP which then bind to the inactive monomeric form ofribonuclease L (RNase L) leading to its dimerization and subsequentactivation. Activation of RNase L leads to degradation of cellularas well as viral RNA, resulting in the inhibition of proteinsynthesis, thus terminating viral replication. Can mediate theantiviral effect via the classical RNase L-dependent pathway or analternative antiviral pathway independent of RNase L.[CATALYTIC ACTIVITY] 3 ATP = pppA2'p5'A2'p5'A + 2 diphosphate.

Subunit : Homodimer.

Subcellular Location : Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion. Nucleus. Microsome. Endoplasmic reticulum.Note=Associated with different subcellular fractions such asmitochondrial, nuclear, and rough/smooth microsomal fractions.

Post-translational modifications : Myristoylation is not essential for its activity.

Glycosylated. Glycosylation is essential for its activity.

Similarity : Belongs to the 2-* synthase family.

Database links : UniProtKB/Swiss-Prot: P29728.3 

實(shí)驗(yàn)流程:

全、新、優(yōu)、品、好四大特點(diǎn):

2'-5'-寡腺苷酸合成酶2抗體規(guī)格 全:公司提供上萬(wàn)種產(chǎn)品,涵蓋了生物試劑,elisa試劑盒,標(biāo)準(zhǔn)品,培養(yǎng)基,原裝耗材,抗體、培養(yǎng)基、ATCC細(xì)胞等,基本上各種科研所需產(chǎn)品在我司都能找到。

新:產(chǎn)品更新速度較快,基本上每周都有新產(chǎn)品出現(xiàn)。

優(yōu):產(chǎn)品質(zhì)量好,投訴比較少。

好:我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì),產(chǎn)品一旦售出,實(shí)驗(yàn)過(guò)程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時(shí)沒(méi)有任何的后顧之憂。

技術(shù)外包服務(wù):

2'-5'-寡腺苷酸合成酶2抗體規(guī)格 分子生物學(xué):質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué):基因合成、引物合成、基因測(cè)序、載體構(gòu)建等

蛋白工程:原核、哺乳動(dòng)物蛋白表達(dá)系統(tǒng)等

病毒包裝:腺病毒、慢病毒等

抗體工程:磁珠分選、病理染色、WB、ELISAIP、IF、IHC、FACS、Confocal等等

細(xì)胞工程:細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。

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