|
| 產(chǎn)地 | 進口、國產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號 | CS10010 |
| 應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| CAS編號 | |
| 抗體名 | Anti-phospho-Nrf2 (Ser40) |
| 克隆性 | |
| 靶點 | 詳見說明書 |
| 適應(yīng)物種 | 詳見說明書 |
| 形態(tài) | 詳見說明書 |
| 宿主 | 詳見說明書 |
| 亞型 | IgG |
| 標識物 | 詳見說明書 |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated Synthesised phosphopeptide derived from human Nrf2 around the phosphorylation site of Ser40 [DF(p-S)QR] |
磷酸化核因子2相關(guān)因子2(Ser40)抗體規(guī)格 英文名稱 Anti-phospho-Nrf2 (Ser40)
中文名稱 磷酸化核因子2相關(guān)因子2(Ser40)抗體規(guī)格
別 名 Nuclear factor-E2 related factor2; HEBP1; NF E2 related factor 2; NFE2 related factor 2; NFE2L2; Nrf 2; Nuclear factor erythroid 2 related factor 2; Nuclear factor erythroid derived 2 like 2; NF2L2_HUMAN.
產(chǎn)品屬性：
濃 度 1mg/1ml
規(guī) 格 0.1ml/100μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Cow
產(chǎn)品類型 一抗 磷酸化抗體
研究領(lǐng)域 免疫學(xué) 染色質(zhì)和核信號 細胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 激酶和磷酸酶
蛋白分子量 predicted molecular weight: 68kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Nrf2 around the phosphorylation site of Ser40 [DF(p-S)QR]
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
磷酸化核因子2相關(guān)因子2(Ser40)抗體規(guī)格 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor which regulates the expression of many detoxification and antioxidant enzymes. Nrf2 can potentially play a significant role in adaptive responses to oxidative stress. Nrf2 belongs to the Cap N Collar (CNC-bZIP) subfamily of basic /leucine zipper (bZIP) transcription factors.
Function : Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.Subunit : Heterodimer. Forms a ternary complex with PGAM5 and KEAP1. May bind DNA with an unknown protein. Interacts via its leucine-zipper domain with the coiled-coil domain of PMF1.Subcellular Location : Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.Tissue Specificity : Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle.Post-translational modifications : Phosphorylation of Ser-40 by PKC in response to oxidative stress dissociates NFE2L2 from its cytoplasmic inhibitor KEAP1, promoting its translocation into the nucleus (By similarity).Similarity : Belongs to the bZIP family. CNC subfamily.Contains 1 bZIP domain.Database links :UniProtKB/Swiss-Prot: Q16236.3Entrez Gene: 4780 HumanOmim: 600492 HumanSwissProt: Q16236 Human
實驗流程：
全、新、優(yōu)、品、好四大特點：
磷酸化核因子2相關(guān)因子2(Ser40)抗體規(guī)格 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標準品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術(shù)咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。
正在熱銷的相關(guān)產(chǎn)品：
Anti-Caspase-10/FITC 熒光素標記半胱胺酸蛋白酶-10抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Anti-HCCR-1/FITC 熒光素標記人基因/bri3結(jié)合蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh CERK 神經(jīng)酰胺激酶CERK抗體 規(guī)格 0.2ml
Tn-C(Tenascin-C)C-Terminus 腱糖蛋白-C(固生蛋白)C端抗原 0.5mg
IL-13 英文名稱： 白介素13抗體 0.1ml
Rhesus antibody Rh TLR1 Toll樣受體1抗體 規(guī)格 0.1ml
Anti-HCCR-1/FITC 熒光素標記人基因/bri3結(jié)合蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml
VEGFR-3(Vascular Epidemal growth factor receptor-3) 內(nèi)皮細胞生長因子受體-3抗原Multi-class antibodies規(guī)格： 0.5mg
Anti-Phospho-Caspase-9 (Try153) 磷酸化半胱氨酸蛋白酶9抗體Multi-class antibodies規(guī)格： 0.1ml
Rhesus antibody Rh PCGF1 表觀抑制因子Polycomb家族成員PCGFl蛋白抗體 規(guī)格 0.2ml
MMP9 Kit Human 人 MMP-9 / CLG4B / MMP9 ELISA配對抗體 ELISA
TLX3 英文名稱： T細胞同源盒蛋白3抗體 0.2ml
caspase-9 p10 英文名稱： 半胱胺酸蛋白酶蛋白9-p10抗體 0.2ml
Anti-Phospho-Caspase-9 (Try153) 磷酸化半胱氨酸蛋白酶9抗體Multi-class antibodies規(guī)格： 0.1ml
Podoplanin Protein 平足蛋白抗原Multi-class antibodies規(guī)格： 0.5mg
Anti-Bdkrb2/B2R 緩激肽B2受體抗體Multi-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh phospho-AKT1/AKT2(Thr308+Thr309) 磷酸化蛋白激酶B抗體 規(guī)格 0.1ml
MMP-13 濃縮液 0.1ml 進口分裝
Uricase 英文名稱： 尿酸酶 0.1ml
DcR1 英文名稱： 壞死因子配體超家族成員10C 0.1ml
Anti-Bdkrb2/B2R 緩激肽B2受體抗體Multi-class antibodies規(guī)格： 0.2ml
TNFSF4 Protein Cynomolgus 重組食蟹猴 OX-40L / TNFSF4 蛋白 (Fc 標簽)
CNE-2Z 人母系細胞
SERPINC1 Others Cynomolgus 食蟹猴 SerpinC1 / AithrombinIII / ATIII 人細胞裂解液 (陽性對照)
LLC-RFP-puro小鼠Lewis細胞 LLC-RFP-puro mice with Lewis lung cancer cells DMEM+10%Hyclone 滅活血清+2ug/ml puromycin
小鼠胚胎成骨細胞前體細胞;MC3T3-E1
人心室成纖維細胞 (HCFav)( 5×105 ) 293A，人胚腎上皮細胞系(腺病毒包裝級別) Human
CL-0454TE-11(人細胞)5×106cells/瓶×2
HA Others H7N9 甲型 H7N9 (A/Shanghai/2/2013) 血凝素 (Hemagglutinin / HA) 人細胞裂解液 (陽性對照)
人膀胱平滑肌細胞RNAHBdSMC miRNA5 μg
兔眼Tenon's囊成纖維細胞;RYTF 細胞，Hep 3B2.1-7細胞 IR983F細胞，大鼠細胞
人男性正常細胞;Hs68
HA Others H5N1 甲型 H5N1 (A/Hong Kong/483/97) 血凝素 (Hemagglutinin / HA) 人細胞裂解液 (陽性對照)
磷酸化核因子2相關(guān)因子2(Ser40)抗體規(guī)格 TNFSF4 Protein Cynomolgus 重組食蟹猴 OX-40L / TNFSF4 蛋白 (Fc 標簽)
CNE-2Z 人母系細胞
SERPINC1 Others Cynomolgus 食蟹猴 SerpinC1 / AithrombinIII / ATIII 人細胞裂解液 (陽性對照)
LLC-RFP-puro小鼠Lewis細胞 LLC-RFP-puro mice with Lewis lung cancer cells DMEM+10%Hyclone 滅活血清+2ug/ml puromycin
小鼠胚胎成骨細胞前體細胞;MC3T3-E1
人心室成纖維細胞 (HCFav)( 5×105 ) 293A，人胚腎上皮細胞系(腺病毒包裝級別) Human
技術(shù)外包服務(wù):
★磷酸化核因子2相關(guān)因子2(Ser40)抗體規(guī)格 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測序、載體構(gòu)建等
★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細胞工程：細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構(gòu)建、細胞RNAi技術(shù)等等。
|
|
|
|
