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核干細胞因子抗體(鳥嘌呤核苷酸結合蛋白3)費用 英文名稱  Anti-Nucleostemin

中文名稱  核干細胞因子抗體(鳥嘌呤核苷酸結合蛋白3)費用 

別    名 E2 induced gene 3 protein; E2IG3; Estradiol induced nucleotide binding protein; GNL3; Guanine nucleotide binding protein like 3 (nucleolar); Guanine nucleotide binding protein like 3; MGC800; NNP47; Novel nucleolar protein 47; NS; Nucleolar GTP binding protein 3; Nucleostemin; Putative nucleotide binding protein estradiol induced; C77032; GNL3_HUMAN.

產品屬性：

濃    度  1mg/1ml

規(guī) 格  0.1ml/100μg 0.2ml/200μg

抗體來源  Rabbit

克隆類型   polyclonal

交叉反應   Human, Mouse, Rat, Dog, Pig, Cow, Sheep

產品類型   一抗  

研究領域    細胞生物 神經生物學 干細胞 細胞類型標志物

蛋白分子量  predicted molecular weight: 62kDa 

性    狀   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human Nucleostemin

亞    型  IgG

純化方法   affinity purified by Protein A

儲 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

核干細胞因子抗體(鳥嘌呤核苷酸結合蛋白3)費用 產品應用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蠟切片需做抗原修復） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

產品介紹 Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell cycle progression in stem cells and cancer cells.

Function : May be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis.Subunit : Interacts with MDM2; this interaction stabilizes MDM2. Interaction with MDM2 occurs in the nucleoplasm and is triggered by a nucleolar release mechanism, such as mitosis-induced nucleolar disassembly (By similarity). Indirectly interacts with TP53, via MDM2-binding (By similarity).Subcellular Location : Nucleus. Nucleus. nucleolus. Shuttles between the nucleus and nucleolus.Tissue Specificity : Increased levels in lung tissue in cancer patients.Similarity : Belongs to the MMR1/HSR1 GTP-binding protein family.Contains 1 G (guanine nucleotide-binding) domain.Database links : UniProtKB/Swiss-Prot: Q9BVP2.2

實驗流程：

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技術外包服務:

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★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等

★病毒包裝：腺病毒、慢病毒等

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